ABSTRACT
Abstract The Pyroligneous extract is a product from the combustion of plant biomass with applications in the fields of health, industrial chemistry, and agriculture. The discovery of new molecules with therapeutic potential and of natural origin continues to be one of the great challenges for research centres around the world. The following work aims to analyze, through a technological prospection, the use of pyroligneous extracts for therapeutic purposes. To carry out the study, searches were carried out in documents deposited in Brazil, Europe, and the United States and searched on platforms specialized in patents. The number of inventions using pyroligneous extract with therapeutic applications is still quite small, however, innovations have been observed for the treatment of diseases of great clinical relevance such as cancer and hypertension. The systematic mapping of innovations is of great importance for the development of new technologies.
ABSTRACT
Abstract Background Cerebrovascular diseases (CVDs) are the second leading cause of death in Brazil. Objective This study aimed to describe the epidemiological profile and to analyze the spatiotemporal dynamics of mortality from cerebrovascular disease in the elderly in Alagoas from 2000-2016. Methods This is a multilevel ecological study of all deaths from CVD in individuals aged 60 years or older. Data were collected from the Mortality Information System. The variables were submitted to descriptive analysis, trend analysis by Joinpoint Regression method and spatial analysis with Global Moran's and local statistics; 95% confidence interval and significance of 5% were considered in the analysis. Results There were 21,440 deaths in the study period, 50.4% (n=10,797) male, 40.5% (n=8,670) aged ≥ 80 years, 44.5% (n=9,465) of "brown" race, 30.1% (n=6,448) married and 36.5% (n=7,828) with less than four years of schooling. Female and male mortality rates were 460.24/100,000 and 602.23 / 100,000, respectively. An annual decreasing trend of -1.4% (p<0.001) in overall and male mortality was observed from 2007 on. The highest mortality rates were concentrated in the eastern region of Alagoas (Moran's I =0.766288; p=0.01). Twenty-two municipalities were in quadrant Q1 of Moran's scattering diagram and considered priorities. Conclusion Death from CVD in Alagoas occurred equally in men and women in the study period, mostly in individuals of mixed race, married, and with low education attainment. The highest rates were observed in the eastern region of the state . The results highlight the need for public policies aimed at healthy aging in the state. (Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0)
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Cerebrovascular Disorders/mortality , Cerebrovascular Disorders/epidemiology , Socioeconomic Factors , Brazil , Aging , Cerebrovascular Disorders/ethnology , Mortality Registries , Ecological Studies , Multilevel Analysis , Healthy AgingABSTRACT
ABSTRACT Bee pollen results from the mixture of pollen and floral nectar with the salivary substances of bees and has increasingly been used as a food with therapeutic properties. In this study, 30 samples of bee pollen from Apis mellifera apiaries in three mesoregions of Alagoas (Brazil) - Mata Atlântica, South Coast and Caatinga, were collected during the dry season of 2008/09 and analysed. Mata Atlântica and Caatinga had good production of bee pollen. In the same season, Mata Atlântica contained a higher diversity of pollen types for feeding bees with a predominance of herbaceous pollen (63%), whereas the Caatinga samples contained monofloral pollen. Physicochemical data were analysed with the nonparametric Kruskal-Wallis statistical test. The Caatinga samples were analysed to determine their contents of total phenolic compounds (25.85 ± 10.80 mg gallic acid eq/g) and flavonoids (45.62 ± 32.19 mg quercetin eq/g) and their antioxidant activity (for instance, 70.62 ± 4.50% in the DPPH test), which were possibly affected by the environmental conditions of this biome.
RESUMO O pólen apícola resulta da mistura de pólen e néctar floral com substâncias salivares da abelha, e emerge como um alimento com propriedades terapêuticas. Neste trabalho foram analisadas 30 amostras desse material de apiários (Apis mellifera), coletadas durante a estação seca de 2008/09 em três mesorregiões de Alagoas - Mata Atlântica, Costa Sul e Caatinga. A Mata Atlântica e a Caatinga foram regiões boas produtoras de pólen apícola. Na mesma época, a Mata Atlântica apresentou a maior diversidade de tipos de pólen para alimentar abelhas, com predominância de herbáceas (63%), enquanto as amostras de Caatinga foram monoflorais. Os dados físico-químicos foram analisados pelo teste estatístico não paramétrico de Kruskal-Wallis. As amostras da Caatinga se destacaram quanto ao teor de fenóis (25,85 ± 10,80 eq. mg Ácido Gálico/g), flavonoides totais (45,62 ± 32,19 eq. mg Quercetin/g), e atividade antioxidante (através do teste do DPPH, por exemplo, 70,62 ± 4,50%), provavelmente devido à condição ambiental deste bioma.